Dr LOO Say Chye Joachim on “Designer” Particles: A Platform For Revolutionizing Drug Delivery

Dr Loo Say Chye Joachim will be presenting on "Designer" Particles: A Platform For Revolutionizing Drug Delivery at 2.30pm on 21 March 2012 at BioPharma Asia Convention’s on floor Seminar.

The following is a summary of his presentation:

Particulate systems have been extensively used in the delivery of drugs. However, monolithic or single-layered polymeric particles may suffer from several inherent limitations, including initial burst release of drugs, a lack of time-delayed or pulsatile release of drugs and the inability to achieve constant drug release. The development of particulate systems using multi-layered (from double-layered to quadruple-layered, and potentially multilayered) particles with layer localization of drugs can be achieved through a simple, direct and economical one-step fabrication technique. Multi-layered particles possess unique structural attributes and this would offer greater versatility in controlling the drug release kinetics and profiles. In this presentation, the fabrication of multi-layered particles, as carriers of multiple drugs, using this one-step fabrication technique will be presented. At the same time, a novel delivery system that allows for the encapsulation of drug-loaded nanoparticles within a microcapsule will also be presented. The uniqueness of these drug delivery systems for the delivery of multiple drug entities, while overcoming burst release, will be discussed. In summary, drug release profiles and kinetics can be altered by "designing" particles that suit to a particular drug delivery application.

Dr Joachim Loo is currently an Assistant Professor in the School of Materials Science and Engineering, Nanyang Technological University (NTU). He received his Ph.D. (as recipient of the A*STAR Graduate Scholarship) from NTU, and was a Visiting Scientist in Mayo Clinic (MN, USA) before returning as a NTU tenured-track faculty staff in 2006. His research interests include controlled drug delivery particulate systems, Drug-Eluting Balloons (DEB), and nanotoxicology. He had published ~60 international peer-reviewed journal papers, one book chapter and filed seven US patents in these research areas. He has often been invited as a reviewer for a number of premier journals, and serves on the International Editorial Review Board for International Journal of Biomaterials Research and Engineering (IJBRE). He has also been invited as guest speaker for several international conferences and by multi-national corporations, such as 3M. He is currently a Principal Investigator, as well as a collaborator, for several local and international research grants amounting to more than S$10M. He also serves as consultant to several local and international companies, including Abbott Vascular (USA). He has received awards for research, teaching and administration, including the Outstanding Mentor Award and the Teaching Excellence Award 2011, and the Service Recognition Award 2010. Currently, he is also the Programme Manager of the Solar Energy and Solar Fuel Centre under the Energy Research Institute at NTU (ERI@N), and the Chief Principal Investigator/Director of the NTU Solar Fuels Laboratory. Dr. Joachim Loo is also currently serving as Secretary of the Materials Research Society of Singapore (MRS-S), and is a member of the American Nano Society and the ISO/TC 229 Nanotechnology National Working Group (under SPRING Singapore).

Don’t miss this excellent opportunity to learn from Dr Joachim Loo. Come forth and listen to what Dr Loo has to say with regards to ‘Designer’ Particles. Click here to sign up for the on-floor seminars at BioPharma Asia Convention 2012 today! Hurry, on-floor seminar slots are limited to the first 80 participants.

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