Recognising challenges in scale-up of proteins produced from microbial fermentation

Mr Chandrakant Kathote, Sr Director, Mfg, Fermentation derived products, Biocon, India will be presenting on the above topic at Biologic Manufacturing World Asia 2012, part of a series of conferences in the 5th Annual BioPharma Asia Convention 2012, held on 19-22 March at Marina Bay Sands, Singapore.

Mr Chandrakant Kathote is Senior Director of Manufacturing at Biocon Limited and is responsible for the manufacturing operations of microbial fermentation based products at Biocon Limited. He has over 14 years of Industry experience with various fermentation derived products like Insulins, Immunosuppressants, Antibiotics, Statins and Enzymes. In his professional career, he had the opportunity to scale-up over 15 products to the manufacturing facility involving complex fermentation and downstream processes. As he plays a Senior leadership role, his responsibility covers long term capacity planning for products falling into various categories; Biosimilars, Generics and Novel molecules. In the past he served as a panelist in one of the Bioprocess International Conference. Mr Kathote holds a MTech degree in Bioprocess Technology from UICT, Mumbai and is currently completing a General Management program from IIM, Bangalore

Mr Kathote will be speaking on the following topics:

Recognising challenges in scale-up of proteins produced from microbial fermentation
1. Assessing typical scale-up issues in downstream processing for improved operations
2. Recognizing the implications of scale-up issues on manufacturing processes
3. Minimizing scale-up issues with proactive strategies in downstream processing

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