Biologic best-sellers and their biosimilars to keep an eye on

top best selling biologics biosimilars (Robson#)

This list of the top 5 best selling biologics of 2012 just goes to show the success that some biologics are experiencing in the pharma market – but is it all plain sailing ahead for the biologic manufacturers? Biosimilars have the potential to reduce treatment costs and increase accessibility of treatments to populations not able to afford their branded counterparts, and here I thought I'd look at some biosimilars which could be closest to threatening these best-selling branded biologics in the future.

Humira (adalimumab) – (AbbVie – 2012 sales: $9.265 billion)

Boehringer Ingelheim: Completed Phase I trial with BI695501 last year

Remicade (infliximab) – (Johnson & Johnson and Merck & Co – 2012 sales: $8.215 billion)

Celltrion: CT-P13 in Phase III clinical trials in South Korea and UK

Enbrel (etanercept) (Amgen and Pfizer – 2012 sales: $7.963 billion)

Shanghai CP Goujian Pharmaceutical: Etanar launched in Colombia, and Yisaipu launched in China

Cipla: Etacept launched in India (but is it likely to overthrow Enbrel?)

Mycenax Biotech: TuNEX is in Phase III clinical trials in Japan and South Korea

Hanwha Chemical: HD203 is in Phase III clinical trials in South Korea

Rituxan/MabThera (rituximab) – (Roche – 2012 sales: $7.285 billion)

Dr Reddy's Laboratories: Reditux marketed in Bolivia, Chile, Peru and India

Probiomed: Kikuzubam marketed in Bolivia, Chile, Peru and India

Boehringer Ingelheim: Recruiting participants for Phase III trials with BI695500 biosimilar

Herceptin (trastuzumab) – (Roche – 2012 sales: $6.397 billion)

Amgen/Actavis: Plans to progress its biosimilar Herceptin into Phase III trials during 2nd quarter of 2013.

Pfizer: Completed Phase I trial with PF-05280014

Are there any particularly important biosimilars you think I've missed of the list? Why not join our discussion on LinkedIn, or leave a comment below.

If you want to know more about biosimilars, you might be interested in attending the World Biosimilar Congress 2013, 12-13 November 2013, which brings together buyers and sellers from across the biosimilar and biobetter industry.

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