Stem cells have been isolated from all developmental periods of life and are thought to participate in tissue regeneration/repair. Hematopoietic stem cells (HSCs) isolated from bone marrow has been used for years in order to reconstitute the bone marrow of recipients suffering from hematological disorders. Since its initial clinical use 20 years ago, umbilical cord blood (UCB) has been considered an alternative source of HSCs. In addition, it is considered a better source of HSCs due to its ease of collection, more tolerance of HLA mismatches, less graft-versus-host disease, and may be used allogeneically.
There have been various forms of mesenchymal stem cell-like (MSC-like) cells isolated from umbilical cords (UCs). The isolation of umbilical cord lining stem cells (ULSCs) may be of great value for those interested in a possible treatment to several disease/disorders. Unlike umbilical cord blood cells, these cells are unique because they can be expanded to therapeutically relevant numbers and cryopreserved for several different uses.
Download DaVinci Biosciences’ article, titled “An Efficient Approach to Isolation and Characterization of Pre- and Postnatal Umbilical Cord Lining Stem Cells for Clinical Applications”, to find out more about:
- Umbilical cord processing
- Umbilical cord lining explants
- Cell culture
- Colony-forming units (CFU) assay
- Ethics and consent
- Growth kinetics
- Immunocytochemistry (ICC)
- Cell differentiation
- Flow cytometry
Involved in the stem cells industry? You should join us at this year’s Stem Cells Regenerative Medicine Congress, taking place September 15-16 in Boston, MA.
DaVinci Biosciences is dedicated to improving the quality of life for individuals suffering from degenerative disease and injury. Through responsible research and development, they strive to be innovative leaders in biotechnology and regenerative medicine. DaVinci Biosciences is renowned worldwide for their scientific and medical achievements and contributions to the health and well-being of communities.[Image: Joseph Elsbernd – Flickr]