Cell Culture World Congress 2016 interview’s Herve Broly, Vice President Biotech Process Development, Merck Serono SA

Ahead of the Cell Culture World Congress 2016, we spoke to Herve Broly, Vice President Biotech Process Development, Merck Serono SA. Herve addresses what he believes to be the biggest achievements within the industry over the past year and lets us know what we can expect from his participation in Munich next February.

1. What do you think have been the biggest achievements within the cell culture sector in the last 12 months?

–          The modulation of mAb glycan profiles without compromising growth and productivity.

–          The application of mini bioreactors in process characterization and control strategy elaboration.

–          Systems biology tools used to understand and characterize host cell lines and how this can affect cell culture process development.

–          The use of host cell line panels as a toolbox for biosimilar process development.

–          Characterization and quantification of HCPs during the overall process from cell culture to drug substance, impact of parental cell line on the type of HCPs expressed.

 

2. What important points do you hope to convey at the congress and what information can you give me now that delegates can look forward to?

–          Process understanding is now a common request from health authorities. One way to achieving it is the use of advanced experimental designs, which needs the use of high throughput cell culture systems that are responsive and representative of the large manufacturing scale.

 

3. What do you think will be the biggest topic of discussion at this February’s Cell Culture World Congress?

–          Process understanding is now a common request from health authorities. One way to achieving it is the use of advanced experimental designs, which need the use of high throughput cell culture systems that are responsive and representative of the large manufacturing scale.

–          Continuous processing.

For more information on the Cell Culture World Congress 2016, including speakers, agenda and confirmed sponsors, visit the event website: terrapinn.com/CellCulture

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