HELM

HELM for Bioregistration

GSK will be making use of the Pistoia Alliance’s Hierarchical Editing Language for Macromolecules (HELM) notation to represent therapeutic large molecules in its bio-registration system, facilitated by the deployment of Dassault Systèmes BIOVIA’s Biological Registration solution. GSK scientists at sites around the world will use the system.

Molecular Structure Exchange

Across the industry there is a need for an advanced macromolecular structure data exchange format that can be used in support of collaboration and externalization. Collaborations between pharma companies and third parties, in particular with research organizations and CROs, are becoming more commonplace. A standard format and internal representation enables data integrity and streamlined communication with colleagues and collaborators. One of the advantages of adopting HELM for the Biological Registration solution deployed by BIOVIA at GSK is that HELM is already a recognized submission format by the FDA. It was therefore important that GSK’s solution should support HELM so that it would be easy to bring in existing molecules as well as those from collaborators.

“HELM has been evolving and becoming an emerging standard within the industry, so by embracing it we are able to provide applications that enable our customers to manage HELM-based data. They can then share this data with other parties that they collaborate with. It’s about enabling our customers to be successful.” 

Neil Eccles, Senior Product Manager Biologics,
Dassault Systèmes BIOVIA

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