Genzyme to Implement Upstream and Downstream Continuous Bioprocess

A patent has just been filed by Genzyme for a new technology platform that will integrate upstream and downstream bioprocess, creating a fully continuous process for biologics manufacture. Genzyme’s new patent claims to combine an upstream perfusion system with a dual stage chromatography process to extract biologics. The first purification stage being a multi-column chromatography system the second consisting of …

How is the post monoclonal antibodies (mAb) world going to develop in the future of biologics?

  As the pharma industry moves into the future of biologics production what challenges will they be facing? The field of biologics is currently on the brink of a new era of high tech drugs. These new drugs have been engineered to be more efficacious than typical mAbs by having a more targeted structure (i.e. antibody drug conjugates). Recently Amgen …

Protein A alternatives

The Protein A Debate: should we still be looking for alternatives?

Interest in researching a cost effective alternative to Protein A has waned in current years. Should we still be on the lookout for other methods of antibody extraction? Protein A is an essential but costly tool in the manufacture of most monoclonal antibodies (MAb). Protein A makes up approximately 30% of the total cost of production and in the past …

Download: Advances and developments in safety for biologicals

Download this presentation here > The European Antibody Congress  brings together big pharma, big biotech, SME Biotech, academia, regulators and the wider service provider community to discuss the latest R&D and advances in the antibody space – across mAbs, ADCs, bispecifics, multispecifics, and protein scaffolds. At the 2013 event, delegates were fortunate enough to hear from Dr Ralf Holzinger, Director, CONFARMA France SARL, who delivered the …

Malaysia’s Premier Biotechnology Park and Ecosystem

Date: 13 March 2014 Time: 9.00am to 2.30pm Venue: Bio-XCell Biotechnology Park, Nusajaya, Johor, Malaysia              Bio-XCell Biotechnology Park (Bio-XCell) is Malaysia’s premier biotechnology park dedicated to healthcare and industrial biotechnology. The park is strategically located in Nusajaya, within the Iskandar region of Johor, Malaysia.  Bio-XCell offers an environment conducive for the development and manufacturing of biologics, pharmaceuticals, bio-based / …

Download Presentation: From discovery through biologics processes, an ensemble approach to integrated workflows

At last years BioPharma Asia convention we were lucky enough to have Bill Balke, VP Asia Pacific Operations & Informatics, PerkinElmer Informatics present during our drug discovery conference track. Click here to download his presentation > His talk: From discovery through biologics processes, an ensemble approach to integrated workflows covers: Overview Paper trails to electronic management systems Biologics user case …

Presentation: Leveraging on the latest technology to boost productivity in drug manufacturing

At last years BioPharma Asia event , Dr Arvind K Mishra, Jt. President- Corporate QC/QA&RA, Cadila Pharmaceuticals Ltd., India delivered a presentation on:  Leveraging on the latest technology to boost productivity in drug manufacturing Click here to download the presentation Some points covered in this presentation include: What is Sustainable Manufacturing Sustainable Manufacturing – A closed loop view Benchmarking the …

Biologic best-sellers and their biosimilars to keep an eye on

This list of the top 5 best selling biologics of 2012 just goes to show the success that some biologics are experiencing in the pharma market – but is it all plain sailing ahead for the biologic manufacturers? Biosimilars have the potential to reduce treatment costs and increase accessibility of treatments to populations not able to afford their branded counterparts, …

Top 5 Best Selling Biologics of 2012

Which drugs were the biggest sellers last year? That's what Genetic Engineering & Biotechnology News asked when compiling their Top 20 Best Selling Drugs of 2012. Extraordinarily – or perhaps not so – the top 3 of the list were all biologics. Looking at the list of these top 5 selling biologics, you might notice a bit of a rheumatoid/psoriatic …

Download our biologic manufacturing e-book for Asia

The production of biotherapeutics including biologics, vaccines and antibodies is gaining more prominence and emphasis in recent years as the generics market is getting saturated. Download our biologic manufacturing e-book for Asia entitled "Biologic Manufacturing Prospects for Emerging Markets in Asia Pacific" to find out more about the current trends and opportunities for biologic manufacturing in this region. > Click …