Utilization of high-throughput screening in the development of HyCell™ CHO medium

Traditionally, cell culture medium development has primarily incorporated shake flask cultures, which limit the number of tested conditions, the number of replicates, and the ability to incorporate advanced design of experiments (DoE) statistical methods. To overcome these limitations, we investigated the use of high-throughput screening (HTS) equipment in the development and testing of a medium for culturing Chinese hamster ovary …

Cell Culture World Congress 2015

Brochure Available for Cell Culture World Congress

In case you haven’t heard of Cell Culture World, we look at the latest challenges for the upstream sector, the latest technologies and host 20+ interactive sessions for increased networking. Download the programme now for full details. 10 reasons why you should attend: Manuel Carrondo and Alois Jungbauer explore the facility of the future along with other top upstream experts. …

Top 25 Representatives in Bioprocessing

Top 25 Representatives in Bioprocessing

This is the question we asked our subscribers, LinkedIn group members and anyone in our contact network to compile a comprehensive list of the Top 25 Representatives in Bioprocessing, as named by you. Download this ebook now. The following 25 personalities have been chosen based on their career achievements, whether this was ground-breaking discovery and research, or innovation, funding, lifetime dedication …

cell culture

Synthetic Biology: The Future of Cell Culture eBook

Cell culture biologics production is expensive when compared to small molecule development, with a large infrastructure of cell culture-based bioreactors to maintain prior to even generating a product. Likewise, the amount of quality control and care that must be placed into cell line and media development to reduce waste products (among other vital functions) often significantly impacts the time it …

Could Antibodies Provide the Answer to Curing Ebola?

Newly discovered antibody drugs such as ZMAPP could provide a solution to the Ebola epidemic that’s sweeping across the globe. We have known about the capacity of antibodies for modulating the immune system for decades, and there are already hundreds of antibody-based drugs that are used to effectively fight various illnesses such as cancer and autoimmune diseases. ZMAPP has been shown …

Increase in Continuous Processing and Single-Use in Future Biomanufacture Forecast in New Review

A review by Institute for Separation and Process Technology has predicted an increase in the use of single use technologies and continuous processing within the manufacture of biologics in the future. Researchers Jochen Strube, Reinhard Ditz and Petra Gronemeyer, predict that demands for high quality biologics will continue to increase in the coming decades. Decreasing production and imminent patent expirations of ‘blockbuster’ drugs coupled with a …

Genzyme to Implement Upstream and Downstream Continuous Bioprocess

A patent has just been filed by Genzyme for a new technology platform that will integrate upstream and downstream bioprocess, creating a fully continuous process for biologics manufacture. Genzyme’s new patent claims to combine an upstream perfusion system with a dual stage chromatography process to extract biologics. The first purification stage being a multi-column chromatography system the second consisting of …

The Cell Culture World Congress USA is where experts like BPTC gather to network, learn from each other, and discuss the latest cell culture industry developments.

BPTC Shares their Insights on cGMP Manufacturing Using Single-use Bioreactors

The use of production scale, single-use bioreactors for cGMP manufacturing is now an accepted option for production of clinical and even commercial biopharmaceutical products. Early adapters are now routinely using 1,000 – 2,000 L single-use bioreactors to manufacture biopharmaceuticals for use in multiple countries worldwide. As outlined in this whitepaper, single-use bioreactors are being utilized to both add cGMP capacity …

Global cell culture market to grow at 10.27% CAGR by 2018

The global cell culture market will grow at a CAGR of 10.27 percent over the period of 2013-2018, predict analysts in a recently released report. The major driver behind this growth is the increased demand for biopharmaceuticals, particularly with growth in the global biosimilar and follow-on biologic market. Biopharmaceuticals can offer improved efficacy over many traditional medicines, particularly in chronic conditions …